Effect of synthetic cannabinoids (JWH-018) on antibody response to HBV vaccination

Synthetic cannabinoids can affect the immune system and cause some changes in response. The response to Hepatit B vaccine is complex. Studies on hepatitis antibody JWH-018 are extremely limited. main aim of this study was investigate effect anti-HBs Ag before or after Hepatitis vaccination. performed C57BL6 mice (n=25). Mice were divided into 3 groups. Control Group; it immunized Engerix at times 3-week intervals. Group 1; (1 mg/kg) administered once a week for 4 weeks. At end period, 2; 3-weeks intervals with B. period treated Blood samples (3 an interval 2 weeks) collected drug administration. It calculated that means obtained from control group lower than other final measurement within-group higher measures statistically significant (p=0,017). Statistical difference measured first (p=0,018) third measurements (p=0,005) between A total 5 experimental groups died different stages study. In study, use has been shown be effective parameter. We think our very valuable terms proving relationship Anti-Hbs However, more data needed understand causation.